I saw a student today and the directions below did not exactly work so we modified them a bit, I am not sure if this was because of a newer iOS. See the highlighted area for the change.
Go to your Settings
Go to Mail, Contacts, calendars
Choose add an account
Other
Select Exchange/Microsoft Exchange
In the appropriate boxes, enter your Groupwise email address, username, and password
For the server address, enter mobilesync.sayreschool.org
Leave domain empty
Enter your username as your first initial last name
If available, or if prompted, select to use SSL
For the rest of the settings, the default should be used
You
should only select to have the mail and calendar items synced. Don't
choose contacts, as this will attempt to sync the whole Groupwise
address book